Overview

Located on the charming Via Vetulonia in the heart of Rome, Osteria 22quattro invites diners to discover authentic Italian flavors in an intimate setting. This Italian restaurant captures the essence of traditional cuisine with a contemporary touch. The focus here is on quality ingredients, skillfully prepared to highlight the rich flavors of Italy’s culinary heritage.

The menu showcases classics reimagined, with main dishes emphasizing fresh pasta, house-made sauces, and locally sourced produce. Each plate reflects a balance between rustic roots and refined technique, making it an ideal destination for those who appreciate genuine Italian fare beyond the tourist traps.

Osteria 22quattro’s atmosphere is warm and inviting, combining modern design with cozy elements to create a space that is both elegant and approachable. It’s a perfect spot for intimate dinners, family gatherings, or casual meals with friends. The attentive service complements the experience without ever overshadowing the food.

This restaurant appeals to a discerning audience—food enthusiasts and locals who value authenticity and a genuine connection to Italy’s rich gastronomy. With its central Rome location, Osteria 22quattro offers an excellent gateway for experiencing Italian cuisine in a setting that honors tradition while embracing contemporary dining culture.


Amenities & Services

Popular for
Lunch
Dinner
Solo dining
Offerings
Alcohol
Beer
Coffee
Healthy options
Late-night food
Spirits
Wine
Atmosphere
Casual
Trendy

What Customers Say

Николай
Mar 7,2026
5/5
This restaurant pleased me with an excellent selection on the menu, and everything was cooked just wonderfully. You can feel that the products are fresh and of high quality. And I also tried the service that is in the photo and calculated the calorie content of my food. It's so simple! I advise everyone to use this service!
Andrea Taylor
Mar 7,2026
5/5
What a wonderful Osteria. It’s small, but the food was amazing and the waiter was SO patient with us. It was just daily specials, not the menu on the website (not sure if this is just because we were there for lunch) so if your Italian is not great figuring out ahead of time isn’t possible. It was well worth the effort though, my salmon was cooked perfectly.
Olli Selaff
Mar 7,2026
5/5
Very nice and pretty small restaurant with almost 15 places inside plus some outside! Very friendly, good English, card payment! We enjoyed the pasta, meet and salmon very much! If you are around, take the chance!
Patrice Camatta
Mar 7,2026
5/5
The restaurante is small, quiet and still we had an absolute great time. The pasta melts on our mouth the wine was a great combination. The owner/waiter she was super friendly, classy, and warm welcomed us. Our family can be loud sometimes, but is was a delicious night with laughs and great culinary. Thanks
Никита
Mar 7,2026
5/5
I unexpectedly received a bonus on a website (the one shown in the photo) and decided to treat myself to a nice dinner. Went for this truffle pasta — the aroma alone was amazing! The portion was generous, everything tasted fresh and delicious. Thanks to that bonus, the evening felt extra cozy and pleasant.
Grar Zmema
Mar 7,2026
5/5
One of the best restaurant we tried in Rome. Very nice staff, great atmosphere, amazing food.
QUVETTE “Mâini curate oriunde” Chiuvete Mobile
Mar 7,2026
5/5
Lovely restaurant, best pasta we’ve eaten in Rome. Highly recommend!
WanderMuseYing
Mar 7,2026
5/5
A very elegant place. Food is tasty and well presented. Beware that they don’t have English menu

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Location

Opening Hours

Monday 12:30 PM - 03:00 PM 07:30 PM - 11:00 PM
Tuesday 12:30 PM - 03:00 PM 07:30 PM - 11:00 PM
Wednesday 12:30 PM - 03:00 PM 07:30 PM - 11:00 PM
Thursday 12:30 PM - 03:00 PM 07:30 PM - 11:00 PM
Friday 12:30 PM - 03:00 PM 07:30 PM - 11:00 PM
Saturday 12:30 PM - 03:00 PM 07:30 PM - 11:00 PM
Sunday 12:30 PM - 03:00 PM 07:30 PM - 11:00 PM
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